Conformation of Lysozyme Derivatives Modified at Two Carboxyl Groups
نویسندگان
چکیده
منابع مشابه
Conformational Studies on Modified Proteins and Peptides IV. CONFORMATION OF LYSOZYME DERIVATIVES MODIFIED AT TYROSINE OR AT TRYPTOPHAN
Conformational investigations have been carried out on derivatives of lysozyme in which tyrosines 20 and 23 were nitrated (NTa-lysozyme), or in which the nitrotyrosine residues had been reduced to aminotyrosine (ATn-lysozyme). Also, a derivative modified at the 6 tryptophan residues by reaction with 2-nitrophenyl sulfenyl chloride (NPSe-lysozyme) was studied. In optical rotatory dispersion meas...
متن کاملConformational studies on modified proteins and peptides. IV. Conformation of lysozyme derivatives modified at tyrosine or at tryptophan residues.
Conformational investigations have been carried out on derivatives of lysozyme in which tyrosines 20 and 23 were nitrated (NTa-lysozyme), or in which the nitrotyrosine residues had been reduced to aminotyrosine (ATn-lysozyme). Also, a derivative modified at the 6 tryptophan residues by reaction with 2-nitrophenyl sulfenyl chloride (NPSe-lysozyme) was studied. In optical rotatory dispersion meas...
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Bovine mercaptalbumin has been modified at the carboxyl groups by means of I-ethyl-3 (3-dimethylisopropyl) carbodiimide and glycine amide. A stable derivative was obtained after modification of 54 groups. The modified protein differed only slightly from the unmodified one with respect to the optical rotatory dispersion parameters ao, bo and ~. This preparation was studied in the analytical ultr...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1974
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)42391-0